Mutation Nation

mutation nation game
Play Game

Game Information

mutation nation game

The entire nation is infested with a virus that turned everyone into violent mutants! Clean up the town before the virus spreads in Mutation Nation! Beat the vicious mutants into a pulp and show them no mercy and try to survive this challenging beat’em up game!

Mutation Nation is a side-scrolling beat’em up classic arcade game released in 1991. The game starts in the year 2050 when a mad scientist was shut down due to his bizarre biological experiments. Years later, the once laboratory became slums and residence of thousands of people. However, a virus suddenly surfaced and turned everyone infected into vicious mutants. The game features two characters Ricky Hones and Johnny Hart who are fierce fighters who have taken justice in their own hands.

Click inside the screen to activate controls.

Press “Space” key to skip the intro screen. Press “Enter” key on the title screen. Press “A” key to start the game.

Arrow Keys – Move
Enter – Start
Space – Select
“S” Key – A button
“A” Key – B button
“W” Key – C button
“Q” Key – D button

Optional: setup your own custom control keys by clicking on the Keyboard icon within the emulator.

There have been 8,695 plays and 3 likes from 3 votes since 12/02/2016.

Game Reviews


Play Mutation Nation game online in your browser free of charge on Arcade Spot. Mutation Nation is a high quality game that works in all major modern web browsers. This online game is part of the Arcade, Action, Emulator, and Neo Geo gaming categories. Mutation Nation has 3 likes from 3 user ratings. If you enjoy this game then also play games Zombie Mutation and Godzilla - Domination!. Arcade Spot brings you the best games without downloading and a fun gaming experience on your computers, mobile phones, and tablets. New arcade games and the most popular free online games are added every day to the site.